This is a very interesting and creative shot. I think that it might be a bit improved if you were to take your mesh layer and warp it a bit more to the contours of the model's face. I would also possibly try to increase the sharpening/detail of the face, it looks a bit soft. Still, this is highly original and well done!
Interesting idea. I get the title, but I wonder if you could have come up with something stronger. Not docking you for that though. I think the title you have could have worked better if you had more items to support it (the first idea I had was maybe making the background look like PhotoShop or something).
As for the other parts of the image, I think flatter light (almost as if coming from a computer screen, perhaps?) would have worked better with this concept than an on-camera flash. I don't think his expression quite fits either. He looks angry or maybe just put-off, but that's probably not the expression that would be on my face if I was being picked apart pixel by pixel!