A protest against Ringling Brothers Circus, outside of Madison Square Garden.
This was a very busy sidewalk, so the hard part was standing back far enough to include both signs (the MSG sign and the protest banner) and then pressing the shutter in the rare moments when no one was blocking the view.
I used to work for a circus (Carson & Barnes) and they treated their animals 1,000's of times better than their people. I don't know about Ringling though.