The clouds in this photo have a fake look to them, probably as a result of the processing you have applied to it. They look as if they were drawn in. This is especially evident on the left most building. The image also lacks colour. ALl the lights are the same colour in this, and I feel you are too closely cropped in. Some extra sky, and extra water would have helped, with a possibly large view of the overall skyline. This then could have seen some reflections in the water, and the building to the right then not being cropped half off.
A competant image that is crisp, sharp and properly framed and composed - a technical success in every way. From an artistic standpoint, it is very dramatic with interesting details. Each image has to be evaluated on it's own merits and this image sets it'self apart due to it's unigue presentation. A very worthy entry into the challenge and a potential top ten image.
Bright white clouds at night? They seem unnatural.....the haloing around the bottom of the clouds makes me think you edited them separately. Not sure I like that. Other than that, a very fine night shot.