The part of the frame around the nose doesn't look right. The textures of the picture in general seem to be a bit off. Skin seems rough and so does the lipstick for that matter. Very good idea.
I like the desaturation and composition. Lighting is too harsh and hot and is clearly visible in the lipstick holder. It has also caused a problem with loss of detail in parts of the cheeks and glare in the lips. It appears like her nose is running. Finally, the visible hairs around the nostrils and cheek are unsightly.