This was taken on my dining room table with some newspaper clippings, a Sanford yellow highlighter, a tripod, and an AlienBees B800 studio strobe. I focused on the bottom graph in the photo to get the area of sharpness I wanted. I didn't do any cropping in Photoshop, I only inverted the colors and did an unsharp mask of 80% and 0.3 pixels.
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Interesting use of negative. I like that - unusual and atmospheric. But for a really "black, depressing" look I think you needed softer lines and some shadows. Of course they would have had to be lights when you composed the scene. Great concept though - very original.
Nice image I like the DOF. That white area near the top left though invites the eye's attention. You probably didn't intend that but had no control over it either.