The title clicks for me! I'm all for centered subjects, but in this case, it might be more effective to have put that bug on a third to enhance the feeling that it is part of a world and not the end all of the photograph. Still, I like the bug's luminescence!
Little grainy and don't know if the blue colour enhances the pic - after all you could have kept it just as an ordinay coloured bug and still fit the challenge :)
Did love the title though - certainly gave me a chuckle
Well, you've already commented on "doing the out of the ordinary" thing and converting to negative. While you meet the challenge (bug), as a photo, it is not so appealing to me. I love macro and close-up photography, but I mostly like it looking natural. Also, I would've never recognized a finger here if you hadn't said so. On the plus side, I think you have a much more interesting original to work from and not converting to negative would be a big improvement in my mind. After all, it's always cool to catch those bugs on "film", you see so much more of them then you see in real life. :)